Immune
System
January
2016 By Natalia A. Zhevago, MD, PhD
Specialist
in photomedicine and photoimmunology. Institute of Cytology, Russian
Academy of Sciences, St. Petersburg, Russia
THE
EFECT OF BIOPTRON LIGHT THERAPY ON THE IMMUNE SYSTEM
Leading
Russian clinicians have at this point proven the wide therapeutic
potential of BIOPTRON light therapy. It is widely used in rheumatology,
sports medicine, and rehabilitation for treatment of diseases
and traumas of the supportive-locomotion apparatus, in dermatology
and surgery (atopical dermatitis, acne, psoriasis, burns, bedsores,
trophic venous ulcers, diabetic foot, posttraumatic
and post-surgery wounds, etc.), in cardiology (for correction of
metabolic syndrome), in cosmetology and stomatology, etc.
Such wide spectrum of therapeutic effects is due to a diversity
of positive functional changes induced by light in the human body:
stimulation of blood circulation in macro and microvessels, normalization
of its transport functions (including oxygen-transport and detoxification),
anti-inflammatory, immunoregulatory, and analgesic effects.
With BIOPTRONs treatment of many diseases, the involvement
of the immune system is obvious: wound healing, skin pathology,
some diseases of joints and respiratory organs (bronchial asthma),
etc. But the most illustrative example of effect of BIOPTRON light
on immunity is its successful use in treatment and prevention of
so often during winter-autumn seasonal viral diseases of the respiratory
pathways, complicated in some cases by addition of secondary bacterial
infections.
Russian pediatricians have proven that BIOPTRON therapy helps to
prevent disease in 60% of cases during the flu epidemic. At the
first sign of illness, light therapy promotes rapid regression of
symptoms, reduces the risk of complications 1.5 - 2 fold, and in
67% of cases prevents a recurrence of the disease within 6 months.
A course of BIOPTRON therapy leads to complete recovery and significant
improvement in 92% of children, while the effectiveness of drug
therapy does not exceed 70%. Positive changes are noted after the
1st light treatment, while the 2nd or 3rd procedure reduces coughing,
throat hyperemia, improves the nasal breathing, sleeping, appetite,
reduces fatigue and irritability.
Clinical data indicates the positive effect of BIOPTRON light on
bronchial patency, the state of autonomic nervous system, cardiac
activity, etc. Normalization of blood indices (leukocytes count,
level of inflammatory markers and immunoglobulins) was also recorded.
For these reasons, BIOPTRON light therapy can improve the efficacy
of specific vaccination: antibodies are formed faster at the higher
concentration and the period of their activity is longer.
Besides this, an important mechanism of recovery involves the improvement
of blood microcirculation and tissue oxygen supply. BIOPTRON light
therapy has no side effects, no age restrictions, and can be used
from the first hours of child's life. The method is indispensable
for children attending groups (schools and kindergartens), as well
as for the most "unprotected" category of children - suffering
from diabetes, allergies, neurological diseases. Light therapy has
immunomodulatory and anti-inflammatory effects, improves the process
of the organism adaptation.
A pronounced correction of immunity disturbances in parallel with
improvement of clinical parameters was also substantiated by other
Russian authors who used BIOPTRON light in a combination with the
standard treatment at other immune-dependent diseases: of skin (herpetic
infections Herpes zoster, psoriasis, atopical dermatitis
and eczema, etc.), joints (rheumatoid arthritis, Bechterevs
disease), ENT diseases (tonsillitis, maxillary sinusitis, otitis),
etc.
It is to be noted that our own studies of immunological effects,
which were carried out at Institute of Cytology of the Russian Academy
of Sciences, have been performed in most case with participation
of apparently healthy volunteers of both gender, various age, i.e.,
with the mean statistical human population. This fact indicates
a possibility of correction of the immune homeostasis parameters
not only at treatment of some particular pathology, but also in
cases of the absence of pathological changes in the organism and
the usefulness of application of the BIOPTRON light for their prevention.
On the whole, the scientific data allow using the polychromatic
polarized light for correction of the anti-infection and anti-tumor
immunity, for the purpose of prevention and treatment of quite a
few diseases of quit different etiopathogenesis. An increase of
IgA concentration allows using BIOPTRON light to improve protection
of mucosae for purposes of treatment and prevention of the
respiratory tract infections, acute respiratory diseases, etc.,
as well as of allergic pathology that is often accompanied by a
decrease of the IgA level.
A decrease of concentration of circulating immune complexes in blood
seems to be prognostically favorable, as it is one of mechanisms
of the antigen elimination. A decrease in blood of levels of some
pro-inflammatory cytokines (IL-6, IL-12 and TNF-a) prevention of
the massive release of other inflammation factors (IL-1ß)
as well as an increase of the content of anti-inflammatory cytokines
(IL-10 and TGF-ß1) can be an important mechanism of the anti-inflammatory
effect of BIOPTRON light therapy.
Stimulation of the IFN-? production can lead to activation of cellular
immunity (phagocytosis of monocytes/macrophages, cytotoxic activity
of NK-cells and cytotoxicCD8+T-lymphocytes) and on the whole
to enhancement of the anti-viral and anti-tumor defense. The absence
of the effect on the content of IL-1ß and IL-4 (provocateurs
of allergy) allows using BIOPTRON light therapy for treatment of
patients with allergic pathology. The inverse dependence of the
light effects on the initial level of immunological parameters (pre-values)
indicates a regulatory character of its action on the immune system.
We recommend BIOPTRON light therapy to every family for prevention,
treatment and rehabilitation.
SHORT INFORMATION:
BIOPTRON light therapy is a unique method of immunomodulation and
adaptation, is able not only to protect children and adults during
seasonal respiratory infections, but also to support the organism
after surgery, traumas and stress. We also recommend BIOPTRON light
therapy as a preventive treatment of oncological diseases, since
it improves efficacy of anti-tumor immunity.
Reference List, (Dr. Zhevago et al.)
1. Zhevago N.A., Samoilova K.A., Glazanova T.V., Pavlova I.E., Bubnova
L.N., Rosanova O.E., Obolenskaya K.D. Exposures of human body surface
to polychromatic (visible + infrared) polarized light modulate a
membrane phenotype of the peripheral blood mononuclear cells. Laser
Technology. 2002. Vol. 12 (1). P. 7-24.
2. Zhevago N.A., Samoilova K.A., Obolenskaya K.D. The regulatory
effect of polychromatic (visible and infrared) light on human humoral
immunity. Photochemical and Photobiological Sciences 2004.
Vol. 3, ?.1. P.102-108.
3. Bogacheva ON, Samoilova KA, Zhevago NA, Obolenskaia KD, Blinova
MI, Kalmykova NV, Kuz'minykh EV.Enhancement of fibroblast growth
promoting activity of human blood after its irradiation in vivo
(transcutaneously) and in vitro with visible and infrared polarized
light. Tsitologiia. 2004. Vol.46(2).
159-171.
4. Zhevago N.A., Samoilova K.A. Pro- and anti-inflammatory cytokine
content in the human peripheral blood after its transcutaneous and
direct (in vitro) irradiation with polychromatic visible and infrared
light. Photomedicine and Laser Surgery. 2006. Vol.
24(2). P.129-139.
5. Zhevago N.A., Samoilova K.A., Calderhead R.G. Polychromatic light
similar to the terrestrial solar spectrum without its UV component
stimulates DNA synthesis in human peripheral blood lymphocytes in
vivo and in vitro. Photochemistry Photobiology. 2006.
Vol. 82(5). P.1301-1308.
6. Zhirnov V. A., Zhevago N.A, Giga I. V., Danilova-Perley V. I.,
Miloradova, S. N. Modern phototherapy technology in sports medicine,
rehabilitation medicine and rehabilitation. Methodical recommendations.
Manual for doctors // 2006. - 40 p.
7. Zhevago NA, Samoilova KA, Davydova NI, Bychkova NV, Glazanova
TV, Chubukina ZhV, Buiniakova AI, Zimin AA.The efficacy of polychromatic
visible and infrared radiation used for the postoperative immunological
rehabilitation of patients with breast cancer. Vopr Kurortol Fizioter
Lech Fiz Kult. 2012. Vol.4. P.23-32.
8. Samoilova KA, Zimin AA, Buinyakova AI, Makela AM, Zhevago NA.
Regulatory systemic effect of postsurgical polychromatic light (480-3400nm)
irradiation of breast cancer patients on the proliferation of tumor
and normal cells in vitro. Photomedicine and Laser Surgery.
2015. Vol. 33(11). P.555-563.
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Steven Warren - Light Therapy UK. All rights reserved 2005 - 2017.
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